Interval between Intra-Arterial Infusion Chemotherapy and Surgery for Locally Advanced Oral Squamous Cell Carcinoma: Impacts on Effectiveness of Chemotherapy and on Overall Survival

Table 3

Univariate and multivariate analysis of prognostic factors in locally advanced OSCC receiving neoadjuvant IAIC.

	Survival
	Univariate			Multivariate
	HR	95% CI	𝑃 value	HR	95% CI	𝑃 value
Age	0.98	0.95–1.00	0.0890
Differentiation
I	1.00
II + III	1.78	0.97–3.14	0.0616
Sites
Gum	1.00			1.00
Mucosa	2.27	1.11–5.25	0.0235	2.08	1.02–4.84	0.0451
Tongue	2.50	1.01–6.47	0.0477	2.24	0.90–5.83	0.0826
Others	2.93	1.07–7.96	0.0360	2.41	0.88–6.66	0.0865
IAIC-OP interval ≥90	1.95	1.19–3.24	0.0085	1.77	1.07–2.97	0.0259