Salvia miltiorrhiza Injection Ameliorates Renal Damage Induced by Lead Exposure in Mice

Figure 3

Effects of SM injection on histopathological changes stained with H&E. Representative microscopic photographs of kidney stained with H&E (magnification 400x). Compared to the normal morphology of kidneys in the control group, those of mice treated with Pb acetate displayed marked histological changes in the cortex and remarkable swelling in the proximal tubular epithelial cells, as well as diminishing glomeruli of the kidney. Although SM-treated mice showed some enlargement of proximal tubular epithelial cells, the glomerulus architecture was normal compared with the Pb group.