Clinical Study
Autoimmune Complications after Hematopoietic Stem Cell Transplantation in Children with Nonmalignant Disorders
Table 1
Patient characteristics.
| | Indication for HSCT | Metabolic disorders | PIDs | HGP | FHL | Fanconi and
SAA | Risk factors |
| | Number of Patients | 10 | 19 | 51 | 4 | 8 | | | AIC, (%) | | | | | | | AICP
ITP + thrombocytopenia | | 1 (5.3) | 5 (9.8) | | | ABO and sex-mismatched graft, metabolic disorder | | Leukopenia | | 1 (5.3) | 2 (3.9) | | | | AIHA | 2 (20) | | 4 (7.8) | | | | AA | | | 1 (1.96) | | 1 (12.5) | | AITD | 1 (10) | 1 (5.3) | | | | Hypogammaglobulinemia metabolic disease, association with other ILCs | | AIH | 1 (10) | 0 | 0 | 0 | 0 | Metabolic disease | | Scleroderma | 0 | 0 | 5 (9.8) | 0 | 0 | HGP, age, chronic GVHD, PBSC, unrelated donor | | Vitiligo | 0 | 2 (10.5) | 4 (7.8) | 0 | 0 |
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PID: primary immunodeficiency disorder; HGP: hemoglobinopathy; FHL: familial hemophagocytic lymphohistiocytosis; AIC: autoimmune complication; AICP: autoimmune cytopenia; ITP: idiopathic thrombocytopenic purpura; AIHA: autoimmune hemolytic anemia; AA: aplastic anemia; AITD: autoimmune thyroid disease; AIH: autoimmune hepatitis.
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