Optimization (Central Composite Design) and Validation of HPLC Method for Investigation of Emtricitabine Loaded Poly(lactic-co-glycolic acid) Nanoparticles: In Vitro Drug Release and In Vivo Pharmacokinetic Studies
Figure 3
Three-dimensional graph showing (a) the effect of mobile phase and methanol concentration on retention time. (b) Three-dimensional graph showing the effect of mobile phase and methanol concentration on peak resolution. (c) Three-dimensional graph showing the effect of mobile phase and methanol concentration on peak asymmetry.