Research Article

Optimization (Central Composite Design) and Validation of HPLC Method for Investigation of Emtricitabine Loaded Poly(lactic-co-glycolic acid) Nanoparticles: In Vitro Drug Release and In Vivo Pharmacokinetic Studies

Figure 3

Three-dimensional graph showing (a) the effect of mobile phase and methanol concentration on retention time. (b) Three-dimensional graph showing the effect of mobile phase and methanol concentration on peak resolution. (c) Three-dimensional graph showing the effect of mobile phase and methanol concentration on peak asymmetry.
583090.fig.003a
(a)
583090.fig.003b
(b)
583090.fig.003c
(c)