Research Article
Stability of Ceftiofur Sodium and Cefquinome Sulphate in Intravenous Solutions
Table 2
Stability of cefquinome sulphate stored in poly(vinyl chloride) minibags.
| 22°C | 6°C | Intravenous solution | t
(day) | c (%) |
Intravenous solution | t (day) | c (%) |
| Water for injection | 0 | 100.00 | Water for injection | 0 | 100.00 | 1 | 98.28 | 1 | 98.52 | 3 | 96.42 | 3 | 96.53 | 6 | 91.93 | 9 | 91.92 |
| Sodium chloride 9 μg/mL | 0 | 100.00 | Sodium chloride 9 μg/mL | 0 | 100.00 | 1 | 99.50 | 1 | 98.24 | 3 | 99.90 | 3 | 96.30 | 6 | 99.84 | 9 | 91.42 |
| Glucose 0.05 mg/mL | 0 | 100.00 | Glucose 0.2 mg/mL | 0 | 100.00 | 1 | 98.20 | 1 | 98.12 | 3 | 89.75 | 3 | 95.02 | 6 | 78.88 | 9 | 90.81 |
| Glucose 0.1 mg/mL | 0 | 100.00 | Glucose 0.1 mg/mL | 0 | 100.0 | 1 | 94.73 | 1 | 98.53 | 3 | 85.69 | 3 | 96.30 | 6 | 75.34 | 9 | 89.99 |
| Glucose 0.2 mg/mL | 0 | 100.00 | Glucose 200 g/L | 0 | 100.00 | 1 | 96.46 | 1 | 98.30 | 3 | 91.14 | 3 | 96.15 | 6 | 82.41 | 9 | 92.10 |
| Mixture of 9 μg/L sodium chloride and 0.05 mg/mL glucose (1 : 1/) | 0 | 100.00 | Mixture of 9 μg/mL sodium chloride and 0.05 mg/mL glucose (1 : 1 /) | 0 | 100.00 | 1 | 99.48 | 1 | 99.72 | 3 | 96.41 | 3 | 97.32 | 6 | 91.01 | 9 | 96.41 |
| Mixture of 9 μg/mL sodium chloride and 0.05 mg/mL glucose (1 : 2 /) | 0 | 100.00 | Mixture of 9 μg/mL sodium chloride and 0.05 mg/mL glucose (1 : 2 /) | 0 | 100.00 | 1 | 96.41 | 1 | 99.55 | 3 | 92.06 | 3 | 98.38 | 6 | 81.73 | 9 | 92.27 |
| Solutio Ringeri | 0 | 100.00 | Solutio Ringeri | 0 | 100.00 | 1 | 97.89 | 1 | 99.78 | 3 | 92.27 | 3 | 97.58 | 6 | 82.86 | 9 | 91.99 |
| Solutio Ringeri Lactate | 0 | 100.00 | Solutio Ringeri Lactate | 0 | 100.00 | 1 | 97.88 | 1 | 98.66 | 3 | 92.70 | 3 | 98.44 | 6 | 86.12 | 9 | 93.56 |
| Multielectrolytic isotonic fluid | 0 | 100.00 | Multielectrolytic isotonic fluid | 0 | 100.00 | 1 | 98.14 | 1 | 99.95 | 3 | 95.72 | 3 | 98.11 | 6 | 92.13 | 9 | 95.13 |
| Pediatric fluid | 0 | 100.00 | Pediatric fluid | 0 | 100.00 | 1 | 97.13 | 1 | 98.16 | 3 | 93.88 | 3 | 96.16 | 6 | 87.81 | 9 | 93.69 |
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c (%): percent of initial concentration.
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