Research Article

Genome Wide Analysis of Sex Difference in Gene Expression Profiles of Bone Formations Using sfx Mice and BXD RI Strains

Figure 4

Gene network among bone relevant genes, which are upregulated in female while downregulated in female, constructed using expression profiles from spleen of female BXD mouse strains. (a) The 11 nodes in the graph below show the selected traits. All nodes are displayed. The 11 edges between the nodes, filtered from the 55 total edges and drawn as curves, show Pearson correlation coefficients greater than 0.35 or less than −0.35. The graph’s canvas is 40.0 by 40.0 cm and the node labels are drawn with a 14.0 point font and the edge labels are drawn with a 10.0 point font. (b) The 31 nodes in the graph below show the selected traits. All nodes are displayed. The 49 edges between the nodes, filtered from the 465 total edges and drawn as curves, show Pearson correlation coefficients greater than 0.4 or less than −0.4. The graph’s canvas is 40.0 by 40.0 cm and the node labels are drawn with a 14.0 point font and the edge labels are drawn with a 14.0 point font. (c) The 43 nodes in the graph below show the selected traits. All nodes are displayed. The 88 edges between the nodes, filtered from the 903 total edges and drawn as curves, show Pearson correlation coefficients greater than 0.4 or less than −0.4. The graph’s canvas is 40.0 by 40.0 cm and the node labels are drawn with a 14.0 point font and the edge labels are drawn with a 14.0 point font.
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(a)
584910.fig.004b
(b)
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(c)