Pioglitazone Upregulates Angiotensin Converting Enzyme 2 Expression in Insulin-Sensitive Tissues in Rats with High-Fat Diet-Induced Nonalcoholic Steatohepatitis
Figure 1
Effects of pioglitazone on hepatic steatosis in rats fed a high-fat diet. Hepatic histopathological changes in the normal control (a) and pioglitazone control (c) groups were within normal limits. Severe hepatic steatosis was found in the high-fat diet group (b). Hepatic steatosis was significantly improved in the high-fat diet plus pioglitazone group (d). (Haematoxylin and eosin; original magnification ×10.)
