Overexpression of DcR3 and Its Significance on Tumor Cell Differentiation and Proliferation in Glioma

Table 2

Relationship between LIs of Ki-67, PCNA, and pathological parameters (𝑥±𝑠).

Parameters	Ki-67	PCNA
Tissue
Normal brain (𝑛=18)	0.09±0.04	0.04±0.02
Glioma (𝑛=125)	13.59±1.16	11.8±1.02
Grade
Low (𝑛=49)	1.40±0.21	1.15±0.17
High (𝑛=76)	21.45±1.23	18.73±1.09
DcR3 expression in glioma
−(𝑛=26)	3.29±1.04	2.78±0.89
+(𝑛=48)	13.63±2.04	11.36±1.70
++(𝑛=32)	15.72±2.06	13.98±1.89
+++(𝑛=19)	24.00±2.06	21.84±1.88

PLIs of Ki-67 and PCNA in normal brain versus low-grade, normal brain versus high-grade, and low-grade versus high-grade: all 𝑃<0.01. Pairwise comparisons of Ki-67 and PCNA LIs between DcR3 (−), (+), (++), and (+++): all 𝑃<0.05.