Effects of Thapsigargin on the Proliferation and Survival of Human Rheumatoid Arthritis Synovial Cells

Figure 3

Thapsigargin inhibits cyclin D1 expression in MH7A cells. ((a)-(b)) Western blots and histograms showing that the cyclin D1 protein levels decreased in MH7A cells by thapsigargin treatment. Results are averages of three independent experiments. Data represent mean ± SEM. ^∗∗𝑃<0.01 and ^∗∗∗𝑃<0.001. (c) Real-time PCR results showing that the cyclin D1 mRNA levels decreased in MH7A cells by thapsigargin treatment. Results are averages of three independent experiments. Data represent mean ± SEM. ^∗∗𝑃<0.01 and ^∗∗∗𝑃<0.001.

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