Gastroprotective Activity of Violacein Isolated from <i>Chromobacterium violaceum</i> on Indomethacin-Induced Gastric Lesions in Rats: Investigation of Potential Mechanisms of Action

<table>Effect of violacein (40 mg/kg, orally) on mucosal PGE<sub>2</sub> level in indomethacin-induced ulcer. Values are mean ± SD (<svg height="11.225" id="M16" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compare vehicle + Indo with all the groups; <svg height="19.65" id="M18" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 70.224998 19.65" width="70.224998" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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<g transform="matrix(.017,-0,0,-.017,11.575,15.5)"><path d="M619 482q0 -69 -40.5 -119t-96 -72.5t-118.5 -26.5h-44l-70 20l-31 -151q-14 -67 0.5 -83t89.5 -22l-5 -28h-287l8 28q65 7 81.5 22t29.5 83l79 398q12 56 0.5 70.5t-78.5 20.5l7 28h255q108 0 164 -43t56 -125zM524 478q0 141 -146 141q-25 0 -47 -8q-16 -6 -20.5 -13.5
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</svg> compare Vio (40 mg) + Indo with SC560 (or) Celecoxib + Vio (40 mg) + Indo. Indo: indomethacin; Vio: violacein.</table>

The Scientific World Journal

fig5

Figure 5

Figure 5: Gastroprotective Activity of Violacein Isolated from <i>Chromobacterium violaceum</i> on Indomethacin-Induced Gastric Lesions in Rats: Investigation of Potential Mechanisms of Action 

Figure 5 | Gastroprotective Activity of Violacein Isolated from Chromobacterium violaceum on Indomethacin-Induced Gastric Lesions in Rats: Investigation of Potential Mechanisms of Action 