Growth Phase-Dependent Proteomes of the Malaysian Isolated Lactococcus lactis Dairy Strain M4 Using Label-Free Qualitative Shotgun Proteomics Analysis

Table 1

List of the proteins identified at the midexponential (ME) and early stationary (ES) growth phases of L.  lactis strain M4.

Gene name	Protein name	ME	ES
	Amino acid biosynthesis
glnA	Glutamine synthetase	•	•
luxS	S-Ribosylhomocysteine lyase	•	•
	Biosynthesis of cofactors, prosthetic groups, and carriers
panE	2-Dehydropantoate-2-reductase	•
trxH	Thioredoxin H-type		•
	Cellular processes
ahpC	Alkyl hydroperoxide reductase subunit C		•
ftsZ	Cell division protein GTPase FtsZ	•	•
divIVA	Cell division initiation protein DivIVA		•
dnaK	Chaperone protein DnaK	•	•
sodA	Superoxide dismutase [Mn]		•
tig	Trigger factor	•	•
	Cell envelope
murD	UDP-N-acetylmuramoylalanine-D-glutamate ligase		•
hasC/galU	UDP-glucose-1-phosphate uridylyltransferase	•	•
	Energy metabolism
pmg	2,3-Bisphosphoglycerate-dependent phosphoglycerate mutase	•	•
pfk	6-Phosphofructokinase	•	•
gnd	6-Phosphogluconate dehydrogenase decarboxylating	•	•
adhE	Alcohol-acetaldehyde dehydrogenase	•	•
enoA	Enolase	•	•
pfl	Formate acetyltransferase	•	•
fbaA	Fructose-bisphosphate aldolase	•	•
pgiA	Glucose-6-phosphate isomerase	•	•
gapB	Glyceraldehyde-3-phosphate dehydrogenase	•	•
ldhA	L-Lactate dehydrogenase 1	•	•
arcB	Ornithine carbamoyltransferase 2	•
pgk	Phosphoglycerate kinase	•	•
enoB	Phosphopyruvate hydratase	•	•
pdhC	Pyruvate dehydrogenase complex E2 component		•
LACR_0691	Pyruvate-formate lyase		•
pyk	Pyruvate kinase	•	•
tpiA	Triosephosphate isomerase	•	•
	Central intermediary metabolism
metK	S-Adenosylmethionine synthase		•
	Fatty acid and phospholipid metabolism
fabF	3-Oxoacyl-acyl carrier protein synthase 2	•	•
fabG1	3-Oxoacyl-acyl carrier protein reductase		•
accB	Acetyl-CoA carboxylase biotin carboxylase subunit		•
acpA	Acyl carrier protein	•	•
fabI	NADH-dependent enoyl-acyl carrier protein reductase		•
	Purines, pyrimidines, nucleosides, and nucleotides
adk	Adenylate kinase	•	•
purA	Adenylosuccinate synthase		•
carB	Carbamoyl phosphate synthase large chain		•
rmlB	dTDP-glucose-4,6-dehydratase		•
rmlA	Glucose-1-phosphate thymidylyltransferase		•
guaA	GMP synthase glutamine hydrolyzing	•	•
guaB	Inosine-5-monophosphate dehydrogenase	•	•
pyrE	Orotate phosphoribosyltransferase	•	•
deoB	Phosphopentomutase	•	•
prsA	Ribose-phosphate pyrophosphokinase		•
prsB	Ribose-phosphate pyrophosphokinase		•
upp	Uracil phosphoribosyltransferase	•	•
pyrH	Uridylate kinase		•
	Regulatory functions
pyrR	Bifunctional protein pyrR	•	•
typA	GTP-binding protein TypA/BipA	•	•
codY	Transcriptional regulator	•	•
codZ	Transcriptional regulator		•
llrC	Two-component system regulator	•	•
	Replication
hslA	Hu-like DNA-binding protein	•	•
	Transcription
rheA	ATP-dependent RNA helicase	•
rpoA	DNA-dependent RNA polymerase alpha subunit	•	•
rpoB	DNA-dependent RNA polymerase beta subunit		•
nusG	Transcription antitermination protein	•
greA	Transcription elongation factor GreA		•
	Translation
rpsA	30S ribosomal protein S1	•	•
rpsB	30S ribosomal protein S2	•	•
rpsC	30S ribosomal protein S3	•	•
rpsD	30S ribosomal protein S4	•	•
rpsE	30S ribosomal protein S5	•	•
rpsF	30S ribosomal protein S6	•	•
rpsG	30S ribosomal protein S7	•	•
rpsH	30S ribosomal protein S8	•	•
rpsI	30S ribosomal protein S9	•	•
rpsJ	30S ribosomal protein S10	•	•
rpsL	30S ribosomal protein S12	•	•
rpsM	30S ribosomal protein S13	•	•
rpsN	30S ribosomal protein S14	•	•
rpsP	30S ribosomal protein S16	•	•
rpsR	30S ribosomal protein S18	•	•
rpsS	30S ribosomal protein S19	•
rpsT	30S ribosomal protein S20	•	•
rpsU	30S ribosomal protein S21	•
rplA	50S ribosomal protein L1	•	•
rplB	50S ribosomal protein L2	•	•
rplC	50S ribosomal protein L3	•	•
rplD	50S ribosomal protein L4	•	•
rplE	50S ribosomal protein L5	•	•
rplF	50S ribosomal protein L6	•	•
rplL	50S ribosomal protein L7/L12	•	•
rplJ	50S ribosomal protein L10	•	•
rplK	50S ribosomal protein L11	•	•
rplM	50S ribosomal protein L13	•	•
rplO	50S ribosomal protein L15	•	•
rplP	50S ribosomal protein L16	•	•
rplQ	50S ribosomal protein L17	•	•
rplR	50S ribosomal protein L18	•	•
rplS	50S ribosomal protein L19	•	•
rplT	50S ribosomal protein L20		•
rplU	50S ribosomal protein L21	•	•
rplV	50S ribosomal protein L22	•	•
rplW	50S ribosomal protein L23	•	•
rpmA	50S ribosomal protein L27	•
rpmB	50S ribosomal protein L28	•	•
rpmC	50S ribosomal protein L29	•	•
rpmD	50S ribosomal protein L30	•	•
rpmE2	50S ribosomal protein L31 type B	•	•
rpmF	50S ribosomal protein L32	•	•
rpmG1	50S ribosomal protein L33 1	•
rpmJ	50S ribosomal protein L36	•	•
pepC	Aminopeptidase C		•
pepN	Aminopeptidase N	•	•
argS	Arginyl-tRNA synthetase	•	•
pepV	Dipeptidase		•
fusA	Elongation factor G	•	•
efp	Elongation factor P		•
tsf	Elongation factor Ts	•	•
tuf	Elongation factor Tu	•	•
ileS	Isoleucyl-tRNA synthetase	•
pepT	Peptidase T		•
ppiB	Peptidyl-prolyl cis-trans isomerase	•	•
pheT	Phenylalanyl-tRNA synthetase beta chain		•
pepQ	Proline dipeptidase	•	•
pepO	Prolidase		•
frr	Ribosome recycling factor	•	•
serS	Seryl-tRNA synthetase	•	•
thrS	Threonyl-tRNA synthetase	•
infA	Translation initiation factor IF-1		•
tyrS	Tyrosyl-tRNA synthetase	•
LACR_1813	Xaa-Pro aminopeptidase		•
	Transport and binding proteins
ptsl	Phosphoenolpyruvate protein phosphotransferase	•	•
malE	Maltose ABC transporter substrate binding protein		•
	Other categories
clpB	ClpB protein		•
cspE	Cold shock protein E	•	•
grpE	Stress response protein E	•
	Hypothetical proteins
yhjA	General stress protein, CsbD superfamily		•
ytjD	Nitroreductase family protein		•
llmg_1773	Putative uncharacterized protein	•	•
llmg_2049	Putative uncharacterized protein	•
SA8A11-2	SA8A11-2 protein		•
LACR_1462	UDP-glucose pyrophosphorylase	•