Research Article
Facile and Promising Method for Michael Addition of Indole and Pyrrole to Electron-Deficient trans-β-Nitroolefins Catalyzed by a Hydrogen Bond Donor Catalyst Feist’s Acid and Preliminary Study of Antimicrobial Activity
Table 4
Antimicrobial activity of the newly synthesized compounds against the pathological strains based on well diffusion assaya.
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Antimicrobial activities were expressed as inhibition diameter zones in millimeters (mm) as follows: N.A. (no activity) ≤ 4 mm; + (weak) = 5–9 mm; ++ (moderate) = 10–15 mm; +++ (strong) = 16–20 mm; and ++++ (very strong) ≥ 21 mm. The experiment was carried out in triplicate and the average zone of inhibition was calculated. |