Clinical and Renal Biopsy Findings Predicting Outcome in Renal Thrombotic Microangiopathy: A Large Cohort Study from a Single Institute in China

Table 4

Univariate renal survival analysis of patients with thrombotic microangiopathy.

Parameters	HR	95% CI		value
		Lower	Upper
Age (years)	0.982	0.956	1.009	0.196
Gender (female versus male)	0.319	0.169	0.602	0.001
Serum creatinine score	4.002	1.709	9.371	0.001
Proteinuria (g/24 hr)	0.991	0.920	1.068	0.820
Plasma albumin value (g/L)	0.994	0.952	1.037	0.765
Hematuria	1.327	0.777	2.265	0.301
Hemoglobin score	1.659	1.183	2.326	0.003
Platelet score	0.897	0.530	1.516	0.684
Neurological involvement	2.171	0.783	6.017	0.136
Modified Rose score	1.354	1.134	1.616	0.001
Presence of acute renal TMA pathologic changes	1.175	0.641	2.156	0.602
Presence of chronic renal TMA pathologic changes	2.709	1.327	5.532	0.006
Isolated glomerular TMA pathologic changes	0.232	0.057	0.953	0.043
Isolated artery/arteriole TMA pathologic changes	2.104	1.061	4.173	0.033
Use of ACEI or ARB	1.702	0.978	2.962	0.060

Notes: ACEI: angiotensin-converting enzyme inhibitors; ARB: angiotensin II receptor blockers.