The Scientific World Journal / 2014 / Article / Fig 5

Research Article

Direct and Indirect Suppression of Interleukin-6 Gene Expression in Murine Macrophages by Nuclear Orphan Receptor REV-ERBα

Figure 5

Peritoneal macrophages from rev-erbα −/− mice increase il6 gene expression. Peritoneal macrophages were harvested as adherent cells from 2-month-old rev-erbα −/− mice and their wild-type (+/+) mice. The cells were treated with or without 1 μg/mL LPS for 24 h. The gene expression of il6 was analyzed by qPCR. For normalization, actb mRNA was used. The data are presented as the means ± S.E. (). versus rev-erbα +/+ mice.

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