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The Scientific World Journal
Volume 2014, Article ID 686493, 6 pages
http://dx.doi.org/10.1155/2014/686493
Review Article

Phantom Eye Syndrome: A Review of the Literature

Department of Dental Materials and Prosthodontics, Araçatuba Dental School, São Paulo State University (UNESP), José Bonifácio 1193, 16015-050 Araçatuba, SP, Brazil

Received 2 September 2014; Revised 17 November 2014; Accepted 20 November 2014; Published 7 December 2014

Academic Editor: Peter Schwenkreis

Copyright © 2014 Agda M. Andreotti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. M. Ahn, S. Y. Lee, and J. S. Yoon, “Health-related quality of life and emotional status of anophthalmic patients in Korea,” American Journal of Ophthalmology, vol. 149, no. 6, pp. 1005-e1–1011-e1, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. D. M. Moshfeghi, A. A. Moshfeghi, and P. T. Finger, “Enucleation,” Survey of Ophthalmology, vol. 44, no. 4, pp. 277–301, 2000. View at Publisher · View at Google Scholar · View at Scopus
  3. I. A. Chaudhry, H. S. Alkuraya, F. A. Shamsi, E. Elzaridi, and F. C. Riley, “Current indications and resultant complications of evisceration,” Ophthalmic Epidemiology, vol. 14, no. 2, pp. 93–97, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. I. Rahman, A. E. Cook, and B. Leatherbarrow, “Orbital exenteration: a 13 year Manchester experience,” British Journal of Ophthalmology, vol. 89, no. 10, pp. 1335–1340, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. P. L. Custer and C. E. Reistad, “Enucleation of blind, painful eyes,” Ophthalmic Plastic & Reconstructive Surgery, vol. 16, no. 5, pp. 326–329, 2000. View at Publisher · View at Google Scholar · View at Scopus
  6. M. L. Rasmussen, J. U. Prause, M. Johnson, F. Kamper-Jørgensen, and P. B. Toft, “Review of 345 eye amputations carried out in the period 1996–2003, at Rigshospitalet, Denmark,” Acta Ophthalmologica, vol. 88, no. 2, pp. 218–221, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. G. E. Rose and J. E. Wright, “Exenteration for benign orbital disease,” British Journal of Ophthalmology, vol. 78, no. 1, pp. 14–18, 1994. View at Publisher · View at Google Scholar · View at Scopus
  8. M. L. R. Rasmussen, “The eye amputated—consequences of eye amputation with emphasis on clinical aspects, phantom eye syndrome and quality of life,” Acta Ophthalmologica, vol. 88, no. 2, pp. 1–26, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Shoamanesh, N. K. Pang, and J. H. Oestreicher, “Complications of orbital implants: a review of 542 patients who have undergone orbital implantation and 275 subsequent peg placements,” Orbit, vol. 26, no. 3, pp. 173–182, 2007. View at Publisher · View at Google Scholar · View at Scopus
  10. M. L. R. Rasmussen, J. U. Prause, M. J. Ocularist, and P. B. Toft, “Phantom eye syndrome: types of visual hallucinations and related phenomena,” Ophthalmic Plastic & Reconstructive Surgery, vol. 25, no. 5, pp. 390–393, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Nicolodi, R. Frezzotti, A. Diadori, A. Nuti, and F. Sicuteri, “Phantom eye: features and prevalence. The predisposing role of headache,” Cephalalgia, vol. 17, no. 4, pp. 501–504, 1997. View at Publisher · View at Google Scholar · View at Scopus
  12. P. Sörös, O. Vo, I.-W. Husstedt, S. Evers, and H. Gerding, “Phantom eye syndrome: its prevalence, phenomenology, and putative mechanisms,” Neurology, vol. 60, no. 9, pp. 1542–1543, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. P. Sörös, O. Vo, H. Gerding, I. W. Husstedt, and S. Evers, “Enucleation and development of cluster headache: a retrospective study,” BMC Neurology, vol. 5, article 6, 2005. View at Publisher · View at Google Scholar
  14. V. S. Ramachandran and W. Hirstein, “The perception of phantom limbs. The D. O. Hebb lecture,” Brain, vol. 121, no. 9, pp. 1603–1630, 1998. View at Publisher · View at Google Scholar · View at Scopus
  15. A. J. Maloof, “hantom vision: a graphic description,” Ophthalmic Plastic and Reconstructive Surgery, vol. 20, no. 1, pp. 80–81, 2004. View at Publisher · View at Google Scholar · View at Scopus
  16. G. J. Menon, I. Rahman, S. J. Menon, and G. N. Dutton, “Complex visual hallucinations in the visually impaired: the Charles Bonnet Syndrome,” Survey of Ophthalmology, vol. 48, no. 1, pp. 58–72, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. F. Wilkinson, “Auras and other hallucinations: windows on the visual brain,” Progress in Brain Research, vol. 144, pp. 305–320, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. H. W. Kolmel, “Complex visual hallucinations in the hemianopic field,” Journal of Neurology Neurosurgery and Psychiatry, vol. 48, no. 1, pp. 29–38, 1985. View at Publisher · View at Google Scholar · View at Scopus
  19. A. M. Santhouse, R. J. Howard, and D. H. Ffytche, “Visual hallucinatory syndromes and the anatomy of the visual brain,” Brain, vol. 123, part 10, pp. 2055–2064, 2000. View at Publisher · View at Google Scholar · View at Scopus
  20. M. Bone, P. Critchley, and D. J. Buggy, “Gabapentin in postamputation phantom limb pain: a randomized, double-blind, placebo-controlled, cross-over study,” Regional Anesthesia and Pain Medicine, vol. 27, no. 5, pp. 481–486, 2002. View at Publisher · View at Google Scholar · View at Scopus
  21. N. Attal, G. Cruccu, R. Baron et al., “EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision,” European Journal of Neurology, vol. 17, no. 9, pp. 1113–e88, 2010. View at Google Scholar
  22. H. Flor, “Phantom-limb pain: characteristics, causes, and treatment,” The Lancet Neurology, vol. 1, no. 3, pp. 182–189, 2002. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Wolff, E. Vanduynhoven, M. van Kleef, F. Huygen, J. E. Pope, and N. Mekhail, “Phantom pain,” Pain Practice, vol. 11, no. 4, pp. 403–413, 2011. View at Publisher · View at Google Scholar · View at Scopus
  24. L. Nikolajsen and T. S. Jensen, “Phantom limb pain,” British Journal of Anaesthesia, vol. 87, no. 1, pp. 107–116, 2001. View at Publisher · View at Google Scholar · View at Scopus
  25. K. Sato, H. Higuchi, and Y. Hishikawa, “Management of phantom limb pain and sensation with milnacipran,” Journal of Neuropsychiatry and Clinical Neurosciences, vol. 20, no. 3, article 368, 2008. View at Google Scholar · View at Scopus
  26. J. Schneider, A. Hofmann, C. Rost, and F. Shapiro, “EMDR in the treatment of chronic phantom limb pain,” Pain Medicine, vol. 9, no. 1, pp. 76–82, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. C. de Roos, A. C. Veenstra, A. de Jongh et al., “Treatment of chronic phantom limb pain using a trauma-focused psychological approach,” Pain Research and Management, vol. 15, no. 2, pp. 65–71, 2010. View at Google Scholar · View at Scopus
  28. M. L. Rasmussen, J. U. Prause, and P. B. Toft, “Phantom pain after eye amputation,” Acta Ophthalmologica, vol. 89, no. 1, pp. 10–16, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. M. A. Hanley, M. P. Jensen, D. G. Smith, D. M. Ehde, W. T. Edwards, and L. R. Robinson, “Preamputation pain and acute pain predict chronic pain after lower extremity amputation,” The Journal of Pain, vol. 8, no. 2, pp. 102–109, 2007. View at Publisher · View at Google Scholar · View at Scopus
  30. H. Gerding, O. Vo, I. W. Husstedt, S. Evers, and P. Sörös, “Phantom pain after enucleation,” Ophthalmologe, vol. 100, no. 11, pp. 943–949, 2003. View at Publisher · View at Google Scholar · View at Scopus
  31. T. S. Jensen, B. Krebs, J. Nielsen, and P. Rasmussen, “Immediate and long-term phantom limb pain in amputees: incidence, clinical characteristics and relationship to pre-amputation limb pain,” Pain, vol. 21, no. 3, pp. 267–278, 1985. View at Publisher · View at Google Scholar · View at Scopus
  32. S. A. Weiss and B. Lindell, “Phantom limb pain and etiology of amputation in unilateral lower extremity amputees,” Journal of Pain and Symptom Management, vol. 11, no. 1, pp. 3–17, 1996. View at Publisher · View at Google Scholar · View at Scopus
  33. H. Flor, “Painful memories. Can we train chronic pain patients to “forget” their pain?” EMBO Reports, vol. 3, no. 4, pp. 288–291, 2002. View at Publisher · View at Google Scholar · View at Scopus
  34. J. Katz and R. Melzack, “Pain “memories” in phantom limbs: review and clinical observations,” Pain, vol. 43, no. 3, pp. 319–336, 1990. View at Publisher · View at Google Scholar · View at Scopus
  35. P. Gallagher, D. Allen, and M. Maclachlan, “Phantom limb pain and residual limb pain following lower limb amputation: a descriptive analysis,” Disability and Rehabilitation, vol. 23, no. 12, pp. 522–530, 2001. View at Publisher · View at Google Scholar · View at Scopus
  36. L. Nikolajsen, S. Ilkjær, K. Krøner, J. H. Christensen, and T. S. Jensen, “The influence of preamputation pain on postamputation stump and phantom pain,” Pain, vol. 72, no. 3, pp. 393–405, 1997. View at Publisher · View at Google Scholar · View at Scopus
  37. E. J. Krane and L. B. Heller, “The prevalence of phantom sensation and pain in pediatric amputees,” Journal of Pain and Symptom Management, vol. 10, no. 1, pp. 21–29, 1995. View at Publisher · View at Google Scholar · View at Scopus
  38. T. S. Jensen, B. Krebs, J. Nielsen, and P. Rasmussen, “Phantom limb, phantom pain and stump pain in amputees during the first 6 months following limb amputation,” Pain, vol. 17, no. 3, pp. 243–256, 1983. View at Publisher · View at Google Scholar · View at Scopus
  39. S. D. Shah-Desai, A. G. Tyers, and R. M. Manners, “Painful blind eye: efficacy of enucleation and evisceration in resolving ocular pain,” British Journal of Ophthalmology, vol. 84, no. 4, pp. 437–438, 2000. View at Publisher · View at Google Scholar · View at Scopus
  40. C. M. Mortimer, W. M. Steedman, I. R. McMillan, D. J. Martin, and J. Ravey, “Patient information on phantom limb pain: a focus group study of patient experiences, perceptions and opinions,” Health Education Research, vol. 17, no. 3, pp. 291–304, 2002. View at Publisher · View at Google Scholar · View at Scopus
  41. J. Halbert, M. Crotty, and I. D. Cameron, “Evidence for the optimal management of acute and chronic phantom pain: a systematic review,” Clinical Journal of Pain, vol. 18, no. 2, pp. 84–92, 2002. View at Publisher · View at Google Scholar · View at Scopus
  42. H. Knotkova, R. A. Cruciani, V. M. Tronnier, and D. Rasche, “Current and future options for the management of phantom-limb pain,” Journal of Pain Research, vol. 5, pp. 39–49, 2012. View at Publisher · View at Google Scholar · View at Scopus
  43. C. H. Wilder-Smith, L. T. Hill, and S. Laurent, “Postamputation pain and sensory changes in treatment-naive patients: characteristics and responses to treatment with tramadol, amitriptyline, and placebo,” Anesthesiology, vol. 103, no. 3, pp. 619–628, 2005. View at Publisher · View at Google Scholar · View at Scopus
  44. M. J. M. Alviar, T. Hale, and M. Dungca, “Pharmacologic interventions for treating phantom limb pain,” Cochrane Database of Systematic Reviews, no. 12, Article ID CD006380, 2011. View at Google Scholar · View at Scopus
  45. S. Mishra, S. Bhatnagar, D. Gupta, and A. Diwedi, “Incidence and management of phantom limb pain according to World Health Organization analgesic ladder in amputees of malignant origin,” The American Journal of Hospice & Palliative Care, vol. 24, no. 6, pp. 455–462, 2007. View at Publisher · View at Google Scholar · View at Scopus
  46. F. Willoch, G. Rosen, T. R. Tolle et al., “Phantom limb pain in the human brain: unraveling neural circuitries of phantom limb sensations using positron emission tomography,” Annals of Neurology, vol. 48, no. 6, pp. 842–849, 2000. View at Google Scholar
  47. L. Nikolajsen, H. Gottrup, A. G. D. Kristensen, and T. S. Jensen, “Memantine (a N-methyl-D-aspartate receptor antagonist) in the treatment of neuropathic pain after amputation or surgery: a randomized, double-blinded, cross-over study,” Anesthesia and Analgesia, vol. 91, no. 4, pp. 960–966, 2000. View at Publisher · View at Google Scholar · View at Scopus
  48. J. Mao and L. L. Chen, “Systemic lidocaine for neuropathic pain relief,” Pain, vol. 87, no. 1, pp. 7–17, 2000. View at Publisher · View at Google Scholar · View at Scopus
  49. E. Huse, W. Larbig, H. Flor, and N. Birbaumer, “The effect of opioids on phantom limb pain and cortical reorganization,” Pain, vol. 90, no. 1-2, pp. 47–55, 2001. View at Publisher · View at Google Scholar · View at Scopus
  50. U. Eichenberger, F. Neff, G. Sveticic et al., “Chronic phantom limb pain: the effects of calcitonin, ketamine, and their combination on pain and sensory thresholds,” Anesthesia and Analgesia, vol. 106, no. 4, pp. 1265–1273, 2008. View at Publisher · View at Google Scholar · View at Scopus
  51. B. Subedi and G. T. Grossberg, “Phantom limb pain: mechanisms and treatment approaches,” Pain Research and Treatment, vol. 2011, Article ID 864605, 8 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  52. R. E. Zuniga, C. R. Schlicht, and S. E. Abram, “Intrathecal baclofen is analgesic in patients with chronic pain,” Anesthesiology, vol. 92, no. 3, pp. 876–880, 2000. View at Publisher · View at Google Scholar · View at Scopus
  53. M. L. R. Rasmussen, O. Ekholm, J. U. Prause, and P. B. Toft, “Quality of life of eye amputated patients,” Acta Ophthalmologica, vol. 90, no. 5, pp. 435–440, 2012. View at Publisher · View at Google Scholar · View at Scopus
  54. A. Clarke, N. Rumsey, J. R. O. Collin, and M. Wyn-Williams, “Psychosocial distress associated with disfiguring eye conditions,” Eye, vol. 17, no. 1, pp. 35–40, 2003. View at Publisher · View at Google Scholar · View at Scopus
  55. M. C. Goiato, D. M. dos Santos, L. C. Bannwart et al., “Psychosocial impact on anophthalmic patients wearing ocular prosthesis,” International Journal of Oral and Maxillofacial Surgery, vol. 42, no. 1, pp. 113–119, 2013. View at Publisher · View at Google Scholar · View at Scopus
  56. F. B. Brady, Singular View, The Art of Seeing with One Eye, F. B. Brady, Vienna, Austria, 6th edition, 2004.
  57. D. R. Goulart, E. Queiroz, A. Ú. R. Fernandes, and L. M. de Oliveira, “Psychosocial aspects in the rehabilitation of patients with anophthalmic socket: implications of the use of ocular prosthesis,” Arquivos Brasileiros de Oftalmologia, vol. 74, no. 5, pp. 330–334, 2011. View at Publisher · View at Google Scholar · View at Scopus