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The Scientific World Journal
Volume 2014, Article ID 689456, 7 pages
Research Article

The Influence of Education on Chinese Version of Montreal Cognitive Assessment in Detecting Amnesic Mild Cognitive Impairment among Older People in a Beijing Rural Community

1Dementia Care & Research Center, Peking University Institute of Mental Health (Sixth Hospital), Key Laboratory for Mental Health, Ministry of Health, No. 51 Huayuanbei Road, Beijing 100191, China
2Wuxi Mental Health Center, Wuxi 214151, China
3Beijing Anzhen Hospital, Capital University of Medical Sciences, Beijing 100029, China
4Qingdao Mental Health Center, Qingdao 266034, China
5Department of Psychological Medicine, National University of Singapore, Singapore 117597

Received 27 March 2014; Accepted 26 April 2014; Published 28 May 2014

Academic Editor: Yuan-Han Yang

Copyright © 2014 Shu'aijun Zhou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


To assess the influence of education on the performance of Chinese version of Montreal cognitive assessment (C-MoCA) in relation to the mini-mental state examination (MMSE) in detecting amnesic mild cognitive impairment (aMCI) among rural-dwelling older people C-MoCA and MMSE was administered and diagnostic interviews were conducted among community-dwelling elderly in two villages in Beijing. The performance of C-MoCA and MMSE in detecting aMCI was evaluated by the area under the ROC curve (AUC). Effect size of education on variations in C-MoCA scores was estimated with general linear model. Among 172 study participants (24 cases of aMCI and 148 normal controls), the AUC of C-MoCA was 0.72 (95% CI = 0.62–0.81, cutoff = 20/21), compared to AUC of MMSE of 0.74 (95% CI = 0.64–0.84, cutoff = 26/27). The performance of both C-MoCA and MMSE was especially poorer among those with low (0–6 years) education. After controlling for gender and age, education (η2 = 0.204) had a surpassing effect over aMCI diagnosis (η2 = 0.052) on variations in C-MoCA scores. Among rural older people, the MoCA showed modest accuracy and was no better than MMSE in detecting aMCI, especially in those with low education, due to the overwhelming effect of education relative to aMCI diagnosis on variations in C-MoCA performance.