Synthesis and Antimycobacterial and Photosynthesis-Inhibiting Evaluation of 2-[(E)-2-Substituted-ethenyl]-1,3-benzoxazoles
Figure 2
Dependence of in vitro antitubercular/antimycobacterial activities against three strains determined after 14 days expressed as log(1/MIC (mol/L)) on lipophilicity expressed as log k of 2-[(E)-2-substituted-ethenyl]-1,3-benzoxazoles 1–12: M. tuberculosis My 331/88 (a), M. avium My 330/88 (b), and M. kansasii My 235/80 (c). (Eliminated compound 4 is marked by cross).
