Synthesis and Antimycobacterial and Photosynthesis-Inhibiting Evaluation of 2-[(E)-2-Substituted-ethenyl]-1,3-benzoxazoles
Figure 3
Relationships between PET inhibition log(1/MIC (mol/L)) in spinach chloroplasts and molar volume (MV (cm3)) of individual substituents in 2-[(E)-ethenyl]-1,3-benzoxazole (a) and lipophilicity expressed as log k (b) of selected studied compounds. (Eliminated compounds 6 and 11 are marked by cross; the most active ortho-substituted compound 2 is marked by triangle).