The Scientific World Journal / 2014 / Article / Tab 3

Research Article

Possible Potentiation by Certain Antioxidants of the Anti-Inflammatory Effects of Diclofenac in Rats

Table 3

Effects of diclofenac, -LA, selenite, Vit C, Vit E, or zinc on plasma levels of MDA, hemolysate GSH, and erythrocyte SOD activity in a rat carrageenan-induced paw edema model.

GroupsMDA (nmol/mL) GSH (mg %)SOD (U/g Hb)

Normal (50  L saline)
Carrageenan (50  L of 1% solution)
Diclofenac (5 mg/kg, per os)
-LA (50 mg/kg, IP)
Se (2.5 mg/kg, po)
Vit C (1 g/kg, po)
Vit E (300 mg/kg, po)
ZnSO4 (25 mg/kg, po)

Values are means of 8 rats (±SD).
Value is significantly different from normal control ( ).
Value is significantly different from carrageenan control ( ).
Value is significantly different from diclofenac group ( ).