Design, Synthesis, Characterization, and Computational Studies on Benzamide Substituted Mannich Bases as Novel, Potential Antibacterial Agents

Table 2

Minimum inhibitory concentration (MIC) of the synthesized benzamide substituted Mannich bases against Gram positive and Gram negative bacteria.

Compounds	Minimum inhibitory concentration (MIC) (μg/mL)
	Gram positive bacteria		Gram negative bacteria
	S. aureus	E. faecalis	E. coli	P. aeruginosa
1	12.5	12.5	12.5	12.5
2	12.5	12.5	6.25	12.5
3	12.5	25	6.25	6.25
4	25	12.5	12.5	25
5	12.5	6.25	3.125	6.25
6	6.25	6.25	6.25	12.5
7	3.125	3.125	3.125	6.25
Control	—	—	—	—
Amoxicillin	1.56	1.56	3.125	3.125
Cefixime	6.25	6.25	12.5	6.25