Design, Synthesis, Characterization, and Computational Studies on Benzamide Substituted Mannich Bases as Novel, Potential Antibacterial Agents

<table class="table-group" id="tab7"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left">Compound</td><td align="center">Observed activity</td><td align="center">Predicted activity</td><td align="center">Residual</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left">1</td><td align="center">1.246051</td><td align="center">1.217519</td><td align="center">0.028532</td></tr><tr><td align="left">2</td><td align="center">1.387902</td><td align="center">1.384015</td><td align="center">0.003887</td></tr><tr><td align="left">3</td><td align="center">1.68467</td><td align="center">1.684545</td><td align="center">0.000125</td></tr><tr><td align="left">4</td><td align="center">0.943075</td><td align="center">0.959732</td><td align="center">−0.01666</td></tr><tr><td align="left">5</td><td align="center">1.558762</td><td align="center">1.568366</td><td align="center">−0.0096</td></tr><tr><td align="left">6</td><td align="center">1.387643</td><td align="center">1.388065</td><td align="center">−0.00042</td></tr><tr><td align="left">7</td><td align="center">1.637533</td><td align="center">1.639689</td><td align="center">−0.00216</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Observed and predicted antibacterial activity of synthesized substituted benzamide Mannich bases against <i>Pseudomonas aeruginosa</i>.

The Scientific World Journal

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Table 7

Table 7: Design, Synthesis, Characterization, and Computational Studies on Benzamide Substituted Mannich Bases as Novel, Potential Antibacterial Agents 

Table 7 | Design, Synthesis, Characterization, and Computational Studies on Benzamide Substituted Mannich Bases as Novel, Potential Antibacterial Agents 