In Vivo Healing Potential of Aegle marmelos in Excision, Incision, and Dead Space Wound Models

Table 1

Effect of graded doses of AME on wound breaking strength in incision wound.

Oral treatment; (od × 10 days)	Wound breaking strength; (g)	PIWBS
Control 0.5% CMC	335.0 ± 15.9	0.0
AME 100 mg/kg	408.8 ± 11.4^b	22.0
AME 200 mg/kg	483.8 ± 9.2^c	44.4
AME 400 mg/kg	465.0 ± 10.4^c	38.8
VTE 200 mg/kg	528.8 ± 9.3^c	57.9

Results are mean ± SEM (𝑛=6). Percentage increases in wound breaking strength (PIWBS) = (𝐷_𝑇/𝐷_𝐶−1) × 100, where 𝐷_𝑇 and 𝐷_𝐶 are WBS values of respective AME-treated and control group.
^b𝑃<0.01, ^c𝑃<0.001 compared to control group (statistical analysis was done by one-way analysis of variance followed by Dunnett’s test for multiple comparisons).