Research Article

In Vivo Healing Potential of Aegle marmelos in Excision, Incision, and Dead Space Wound Models

Table 2

Effect of AME and VTE on free radicals (LPO & NO), antioxidants (SOD & GSH), and myeloperoxidase in granulation tissue.

Oral treatment
(mg/kg, od)
AntioxidantsFree radicalsMyeloperoxidase
GSH
nM/mg protein
SOD
IU/mg protein
CAT
mU/mg protein
LPO
nM/mg protein
NO
nM/mg protein
MPO
mU/mg protein

Control (0.5% CMC)27.7 ± 0.980.43 ± 0.0243.1 ± 1.695.82 ± 0.1039.00 ± 1.1923.9 ± 0.43
AME 200 31.3 ± 0.76a0.67 ± 0.05b180.2 ± 0.67c2.62 ± 0.16c17.34 ± 0.63c18.8 ± 0.42c
VTE 200 36.3 ± 1.12c0.81 ± 0.03c211.7 ± 0.95c2.33 ± 0.10c17.75 ± 0.70c15.1 ± 0.58c

Results are mean ± SEM ( ). a , b and c compared to respective control group (statistical analysis was done by one way analysis of variance followed by Dunnett’s test for multiple comparisons).