In Vivo Healing Potential of Aegle marmelos in Excision, Incision, and Dead Space Wound Models
Table 2
Effect of AME and VTE on free radicals (LPO & NO), antioxidants (SOD & GSH), and myeloperoxidase in granulation tissue.
Oral treatment (mg/kg, od)
Antioxidants
Free radicals
Myeloperoxidase
GSH nM/mg protein
SOD IU/mg protein
CAT mU/mg protein
LPO nM/mg protein
NO nM/mg protein
MPO mU/mg protein
Control (0.5% CMC)
27.7 ± 0.98
0.43 ± 0.02
43.1 ± 1.69
5.82 ± 0.10
39.00 ± 1.19
23.9 ± 0.43
AME 200
31.3 ± 0.76a
0.67 ± 0.05b
180.2 ± 0.67c
2.62 ± 0.16c
17.34 ± 0.63c
18.8 ± 0.42c
VTE 200
36.3 ± 1.12c
0.81 ± 0.03c
211.7 ± 0.95c
2.33 ± 0.10c
17.75 ± 0.70c
15.1 ± 0.58c
Results are mean ± SEM (). a, b and c compared to respective control group (statistical analysis was done by one way analysis of variance followed by Dunnett’s test for multiple comparisons).