|
| Gene polymorphism of immune-related genes | |
|
| IFN gamma [147, 148] | |
| TNF [149, 150] | |
| TNF-α receptor 2 [151] | |
| IL-4 (only nonerosive OLP) [147] | |
| IL-6 [150] | |
| Haplotype IV of IL-10 [152] | |
| IL-18 [153] | |
| Tumor suppressor genes (e.g., P53) [154, 155] | |
| HLA-A3 (In a Swedish population with LP [156] and two British populations with LP [157] and with familial LP [158]) | |
| HLA-A5 (in a British population with LP [157]) | |
| HLA-B7 (in a British population with familial LP [158], another study supported against [159]) | |
| HLA-B8 (OLP) [2], a study supported against [159] | |
| HLA-B15 (in a Croatian population with OLP) [160] | |
| HLA-B18 inverse association with OLP in a Croatian population [160] | |
| HLA-Bw35 (CLP) [2] | |
| HLA-Bw57 (in a British population with OLP) [161] | |
| HLA-BW61 (in a Japanese population with OLP) [162] | |
| HLA-DR1 (in wide range of ethnicities) [163–167], in a British population with CLP [167], in an Italian population with LP [168], and in an Arab population with CLP [166] | |
| HLA-DRB1*0101 (in a Sardinian population in Italy with CLP [169] and also with LP in a Mexican Mestizo population [169] and in a British population with CLP [167]), | |
| HLA-DR2 (in an Israeli-Jewish population with erosive OLP) [170], | |
| HLA-DR3 (in a Swedish population with erosive OLP) [171] | |
| HLA-DR9 (in Chinese population with erosive OLP) [172] | |
| HLA-DRW9 (in a Japanese population with OLP) [162] | |
| HLA-DR10 (in an Arab population with CLP) [166] | |
| HLA-DQ1 (in a British population with CLP, [167] inverse association with OLP in a British population [161] | |
| HLA-DQB1*0201 (with vulvovaginal-gingival syndrome in two British populations) [81, 173] | |
| HLA-Te22 (in a Chinese population with erosive OLP) [172]; also it is highly associated with positive antinuclear antibodies in erosive OLP patients [174] | |
| rs2372736, defined at the chromosome 3p14-3q13 [175] | |
|
| Gene polymorphism of other genes | |
|
| Oxidative stress [176–179] | |
| PGE2 [180] | |
| Antithyroglobulin, antithyroid microsomal autoantibody, T3, T4 [181–183] | |
| Prothrombin [184] | |
| Epigenetic-associated genes (DNMT3B) [185] | |
| miRNA-146a [186] and miRNA-155 [186, 187] | |
| Nuclear factor-kappa B p65 [188] | |
|
