Effect of Antrodia camphorata on Inflammatory Arterial Thrombosis-Mediated Platelet Activation: The Pivotal Role of Protein Kinase C

Figure 3

Influence of Antrodia camphorata on PKC activation in activated platelets. ((a) and (c)) Washed platelets were preincubated with 112, 224, or 448 μg/mL of Antrodia camphorata and subsequently treated with 1 μg/mL of collagen or 150 nM PDBu to induce p47 phosphorylation, the PKC downstream ((a) and (c)), and (b) platelet aggregation. Data are presented as the mean ± SEM (; compared with solvent control platelets; and compared with the collagen group). Profiles (b) are representative of 3 independent experiments.

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