Validity of Cardiovascular Risk Prediction Models in Kidney Transplant Recipients

Table 3

Studies excluded from the systematic review and reason for exclusion.

Study	Objective	Outcome	Design	Sample size and inclusion criteria	Follow-up	Scoring system	Summary of results	Reason for exclusion
Gupta et al. [52] 2005	To compare a modified cardiac risk assessment to patients who died versus a group that survived	Death	Retrospective case control; (Newcastle Upon Tyne, United Kingdom)	𝑛=247; 146 cases (death) versus 101 control scores	Charts reviewed from 1996 to 2003	Modified Cardiac Risk Assessment (based on guidelines for perioperative CV evaluation for noncardiac surgery from the ACC/AHA task force)	Deceased group had higher CV risk scores. Correlation between risk score and mortality.	Case-control study design did not meet inclusion criteria; methodological issues
de Pádua Netto et al. [53] 2012	To assess ability of FRS to predict CV events in a population theoretically without risk factors	Unclear	Retrospective cohort study; (Brazil)	𝑛=126; RTR with a functioning graft for >6 months	45 ± 16 years; 65% male (𝑛=82)	Framingham; Charts reviewed from 2005 to 2010	FRS does not adequately quantify real CV risk	Observational only; FRS in this population was assessed, but outcome was poorly described with no clear process defined to meet objective

CV: cardiovascular; ACC: American College of Cardiology; AHA: American Heart Association.