Clinical Study

Evaluation of the Effect of Concurrent Chronic Total Occlusion and Successful Staged Revascularization on Long-Term Mortality in Patients with ST-Elevation Myocardial Infarction

Table 1

Baseline clinical and angiographic characteristics.

Variable SVDMVD, no CTOMVD with CTO value
( = 595, 47.0%)( = 519, 41.0%) ( = 152, 12.0%)

Baseline characteristics
 Age > 60 years250 (42.0%)222 (62.0%)102 (67.1%)<0.01
 Male410 (68.9%)389 (75.0%)121 (79.6%)0.010
 Diabetes mellitus60 (10.1%)98 (18.9%)38 (25.0%)<0.01
 Hypertension262 (44.0%)296 (57.0%)102 (67.1%)<0.01
 Hyperlipidaemia238 (40.0%)234 (45.1%)85 (55.9%)<0.01
 Current smoking310 (52.1%)118 (42.0%)66 (43.4%)<0.01
 Prior MI46 (7.7%)77 (14.8%)47 (30.9%)<0.01
 Prior PCI49 (8.2%)82 (15.8%)44 (28.9%)<0.01
 Cardiogenic shock on admission42 (7.1%)69 (13.3%)36 (23.7%)<0.01
 CrCL (mL/min) <0.01
 history of CHF9 (1.5%)17 (3.3%)10 (6.6%)<0.01
 Family history of CVD (%)250 (42.0%)219 (42.2%)58 (38.2%)0.651
 IABP, (%)24 (4.0%)55 (10.6%)36 (23.7%) <0.001
 Use of GPI, (%)301 (50.6%)257 (49.5%)76 (50.0%)0.938
 LVEF <0.01
 LVEF < 40%, (%)125 (21.0%)134 (25.8%)72 (47.4%)<0.001
Angiographic characteristics
 Single vessel disease595 (100%)0 (0%)0 (0%)
 2-vessel disease0 (0%)315 (60.7%)74 (48.7%)<0.001
 3-vessel disease0 (0%)204 (39.3%)78 (51.3%)<0.001
Infarct-related artery
 LM, (%)1 (0.2%)6 (1.2%)3 (2.0%)0.038
 LAD, (%)253 (42.5%)178 (34.3%)67 (44.1%)0.009
 LCA, (%)72 (12.1%)70 (13.5%)30 (19.7%)0.049
 RCA, (%)269 (45.2%)265 (51.0%)52 (34.2%)0.001
 TIMI flow 3 post-PCI529 (88.9.%)430 (82.9%)119 (78.3%)0.001

Categorical variables are described as absolute numbers (%) and compared by means of the chi-square test; continuous variables are described as mean ± SD and compared by means of the Student’s -test. MI: myocardial infarction; PCI: percutaneous coronary intervention; CrCL: creatinine clearance; CHF: congestive heart failure; CVD: cardiovascular disease. LM: left main coronary artery; LAD: left anterior descending coronary artery; LCA: left circumflex artery; RCA: right coronary artery; TIMI: thrombolysis in myocardial infarction; PCI: percutaneous coronary intervention; IABP: intra-aortic balloon pump; GPI: glycoprotein IIb/IIIa inhibitors; LVEF: left ventricular ejection fraction.