The Effect of Obesity on Brain Diffusion Alteration in Patients with Obstructive Sleep Apnea

Table 2

Mean ADC values (×10⁻⁶ mm²/s) of different brain regions in patients with OSA.

Locations	Group 1 (𝑛=43)			Group 2; (𝑛=22)
	Subgroup 1; (𝑛=16)	Subgroup 2; (𝑛=27)	Total; (𝑛=43)
Dentate nucleus	696.60±29	713.04±25	706.93±27	704.05±13
Cerebellar vermis	724.06±31	744.48±46	736.88±42	721.00±25
Cerebellar cortex	741.00±34	742.22±37	741.77±35	748.73±38
Amygdala	787.75±38	796.19±34	793.05±36	795.23±41
Midbrain	788.50±32	746.22±45	761.95±45	764.36±40
Hippocampal gyrus	831.19±33	828.30±40	829.37±37	812.91±35
Occipital cortex	789.19±26	784.04±26	785.95±26	775.32±31
Hypothalamus	768.69±33^a,b	731.11±31	745.09±36^d	723.45±34
Middle temporal cortex	763.56±36	759.19±44	760.81±41	750.00±51
Insular cortex	814.50±36^b	805.11±29	808.60±32^d	774.82±48
Parietal cortex	792.75±29^a,b	760.11±31	772.26±34^d	750.77±28
Orbitofrontal cortex	795.38±40^a	761.85±38	774.33±41	771.32±40
Cingulate gyrus	794.56±38	788.78±36	790.93±36	785.18±26
Posterior limb of internal capsula	714.56±43	710.89±33	712.26±37^d	691.95±22
Caudate nucleus	730.25±37^b	722.07±22	725.12±28^d	702.64±36
Globus pallidum	745.31±47	737.85±40	740.63±42	730.68±31
Putamen	745.25±27	741.41±36	742.84±32	734.59±26
Thalamus	751.13±46	754.67±31	753.35±36	750.59±30
Optic radiation	781.88±44	780.89±33	781.26±37	769.64±29
Genu of corpus callosum	772.44±46	778.44±38	776.21±41	778.59±42
Splenium of corpus callosum	760.94±58	759.81±51	760.23±53	751.68±47
Dorsomedial frontal cortex	753.38±36	774.11±51	766.40±47	778.73±55
Dorsolateral frontal cortex	755.81±41	769.30±34	764.28±37	796.68±60
Frontal white matter	777.31±38^b,c	770.63±30	773.12±33^d	743.27±32

Group 1: total obese patients (BMI ≥ 30 kg/m²).
Subgroup 1: morbid obese patients.
Subgroup 2: obese patients.
Group 2: nonobese (control) patients.
aSignificant differences between subgroup 1 and subgroup 2.
bSignificant differences between subgroup 1 and group 2.
cSignificant differences between subgroup 2 and group 2.
dSignificant differences between group 1 and group 2.