Research Article

The Inhibitory Effect of a Novel Polypeptide Fraction from Arca subcrenata on Cancer-Related Inflammation in Human Cervical Cancer HeLa Cells

Figure 1

(a) Effects of P2 and LPS on the cell viability of RAW264.7 cells. RAW264.7 cells were treated by P2 and LPS at different concentrations for 24 h and 48 h. Cell viability was determined by MTT assay. The results are representative of three independent experiments and expressed as mean ± SD. Differences were defined as significant at . (b) Effects of P2 on NO production in LPS-stimulated RAW264.7 cells. Cells were stimulated with LPS for 2 h followed by treatment with P2 (15–150 μg/mL) for 48 h. Nitrite in the medium was measured using Griess reagent. *** compared with NC (negative control); # compared with LPS-treatment only. The results are representative of three independent experiments and expressed as mean ± SD. Differences were defined as significant at .
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(a)
768938.fig.001b
(b)