The Inhibitory Effect of a Novel Polypeptide Fraction from Arca subcrenata on Cancer-Related Inflammation in Human Cervical Cancer HeLa Cells
Figure 4
(a) Effects of P2 on immune-related proteins expression in HeLa cells. Following treatment with P2 (1.33, 4, 12 μg/mL), whole lysates were collected and analyzed by western blotting with antibodies specific for COX-2 and iNOS. GAPDH was used as an internal control. Results are representative of three independent experiments. (b) Quantification of expression levels by western blotting. The inhibition of COX-2 and iNOS were 78.67% and 69.65% for the high concentration, respectively, after treatment with P2. GAPDH was used as an internal control. * and ** compared with NC. The results are representative of three independent experiments and expressed as mean ± SD. Differences were defined as significant at .
