The Scientific World Journal / 2014 / Article / Fig 5

Review Article

Overview of Platelet Physiology: Its Hemostatic and Nonhemostatic Role in Disease Pathogenesis

Figure 5

After an injury in the vessel wall, activation of platelets begins to start. It involves its adhesion to the subendothelium surface. Interaction between receptors like GPIb-V-IX, GPIa-IIa, and subendothelial compounds like vWf and collagen triggers the release of platelet granule contents accelerating aggregate formation.

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