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The Scientific World Journal
Volume 2014 (2014), Article ID 783525, 5 pages
http://dx.doi.org/10.1155/2014/783525
Research Article

Influence of Refractive Condition on Retinal Vasculature Complexity in Younger Subjects

1Department of Optometry and Visual Science, Kulliyyah of Allied Health Sciences (KAHS), International Islamic University Malaysia (IIUM), Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia
2Department of Diagnostic Imaging and Radiotherapy, Kulliyyah of Allied Health Sciences (KAHS), International Islamic University Malaysia (IIUM), Bandar Indera Mahkota, 25200 Kuantan, Pahang, Malaysia

Received 24 July 2014; Revised 16 September 2014; Accepted 16 September 2014; Published 13 October 2014

Academic Editor: Ahmad M. Mansour

Copyright © 2014 Mohd Zulfaezal Che Azemin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. The aim of this study was to compare the retinal vasculature complexity between emmetropia, and myopia in younger subjects. Methods. A total of 82 patients ( years) with two types of refractive conditions, myopia and emmetropia were enrolled in this study. Refraction data were converted to spherical equivalent refraction. These retinal images (right eyes) were obtained from NAVIS Lite Image Filing System and the vasculature complexity was measured by fractal dimension (), quantified using a computer software following a standardized protocol. Results. There was a significant difference () in the value of between emmetropic () and myopic () groups. A positive correlation (, ) between the and the spherical equivalent refraction was detected in this study. Using a linear model, it was estimated that 6.7% of the variation in could be explained by spherical equivalent refraction. Conclusions. This study provides valuable findings about the effect of moderate to high myopia on the fractal dimension of the retinal vasculature network. These results show that myopic refraction in younger subjects was associated with a decrease in , suggesting a loss of retinal vessel density with moderate to high myopia.