Review Article

Benefits and Harms of Extending the Duration of Dual Antiplatelet Therapy after Percutaneous Coronary Intervention with Drug-Eluting Stents: A Meta-Analysis

Table 3

Rates of bleeding events in the two groups with different duration of dual antiplatelet therapy.

Study IDTotal number in short duration group Total number in longer duration group Thrombolysis in myocardial infarction major bleeding Gastrointestinal haemorrhage Intracranial haemorrhage Total haemorrhage
ShortLongShortLongShortLongShortLong

Gwon et al. 2012 (EXCELLENT trial) [6]7227212 (0.3%)4 (0.6%)NANANANA4 (0.6%)10 (1.4%)
Hu and Wang 2012 [10]8894NANANANANANANANA
Kim et al. 2012 (RESET trial) [7]1,0591,0582 (0.2%)6 (0.6%)NANANANA510
Park et al. 2010 (REAL-LATE and ZEST-LATE) [8]1,3441,3573 (0.2%)1 (0.1%)NANANANANANA
Valgimigli et al. 2012 (PRODIGY) [9]9839876 (0.6%)16 (1.6%)NANA4 (0.4%)10 (1%)15 (1.5%)27 (2.7%)