QuadraPure-Supported Palladium Nanocatalysts for Microwave-Promoted Suzuki Cross-Coupling Reaction under Aerobic Condition

Table 1

Microwave-promoted Suzuki coupling of aryl halides with phenylboronic acid catalyzed by XL-QPPd nanoparticles.

Entry	R1	X	Yield^b %
1	H	Br	85
2	OMe	Br	90
3	NO2	Br	97
4	CF3	Br	82
5	Me	Br	85
6	COCH3	Br	97
7	H	I	87
8	OMe	I	96
9	H	Cl	18
10	OMe	Cl	23

aReaction condition: phenylboronic acid (0.75 mmol), aryl halide (0.5 mmol), K₂CO₃ (0.75 mmol), XL-QPPd (0.05 mmol), water (2 mL), and microwave, 120°C.
^bBased on the isolated yield of the monosubstituted product after column chromatography on silica gel.