Caloric Restriction Prevents Lead-Induced Oxidative Stress and Inflammation in Rat Liver
Liver glutathione peroxidase (GPx) in ad libitum (AL) andcaloric restriction (CR) groups after lead or saline administrations. Seven days of lead injections (15 mg/Kg body weight, ip) to AL animals caused significant reduction of liver GPx (* compared to the saline-injected AL); in CR animals GPx changes after the same dose lead administration were not significant. Liver GPx content was significantly higher in lead-administered CR compared to lead-administered AL (# compared to the lead-injected AL). The data are presented as means ± SEM.