Research Article

Caloric Restriction Prevents Lead-Induced Oxidative Stress and Inflammation in Rat Liver

Figure 4

Liver malondialdehyde (MDA) in ad libitum (AL) and caloric restriction (CR) groups after lead or saline administrations. Seven days of lead injections (15 mg/Kg body weight, ip) to AL animals caused significant raise of liver MDA (* compared to the saline-injected AL); in CR animals MDA changes after the same dose lead administration were not significant. Liver MDA content was significantly lower in lead-administered CR compared to lead-administered AL (# compared to the lead-injected AL). The data are presented as means ± SEM.