Caloric Restriction Prevents Lead-Induced Oxidative Stress and Inflammation in Rat Liver
Liver malondialdehyde (MDA) in ad libitum (AL) and caloric restriction (CR) groups after lead or saline administrations. Seven days of lead injections (15 mg/Kg body weight, ip) to AL animals caused significant raise of liver MDA (* compared to the saline-injected AL); in CR animals MDA changes after the same dose lead administration were not significant. Liver MDA content was significantly lower in lead-administered CR compared to lead-administered AL (# compared to the lead-injected AL). The data are presented as means ± SEM.