The Scientific World Journal / 2014 / Article / Tab 1

Research Article

Nanospray Drying as a Novel Technique for the Manufacturing of Inhalable NSAID Powders

Table 1

Klys/leu powders produced by nanospray drier: process parameters, yield, drug content, and particle size distribution (15% leu and 30% IPA).

Batch (°C)Total powder concentration (% w/v) Nozzle (µm)Yield (%) (µm) and span Drug content (% p/p)Process time (mL/min)

#11105%787.0 ± 2.86.6 (1.7)79.4 ± 1.51.11
#21103%782.3 ± 3.26.2 (1.7)77.0 ± 2.11.11
#31105%462.3 ± 2.83.2 (1.7)82.9 ± 0.80.13
#41103%443.0 ± 4.2a79.2 ± 3.10.10
#5705%477.6 ± 1.62.4 (1.7)75.3 ± 0.40.06
#6703%456.7 ± 1.0a78.5 ± 1.10.06
#7701%452.1 ± 1.8a80.1 ± 1.30.08
#8605%427.9 ± 7.1a73.5 ± 1.20.04
#9705%5.568.6 ± 1.93.1 (2.4)72.4 ± 0.60.33

Powder stickiness prevented measure.

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