Research Article

The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats

Table 2

Activity of oxidative stress markers (CAT, PON1, FRAP, PCG, and SH) marked in brain tissue homogenates in Wistar rats. Data are presented as means from independent measurements ± standard deviation (SD). Different letters in the same columns indicate significant differences according to Tukey’s test ().

DietCornusCAT-brain
U/mg protein
PON1-brain
U/mg protein
FRAP-brain
mM Fe2+/mg protein
PCG-brain
nM/mg protein
SH-brain
nM/mg protein

C−No65.4 ± 17.9B31.8 ± 14.3AB0.112 ± 0.015A3.4 ± 1.47AB0.225 ± 0.091A
F−No53.5 ± 20.6AB20.7 ± 6.5A0.168 ± 0.044AB4.28 ± 1.37AB0.317 ± 0.089A
Fa−No32.2 ± 13.7A17.1 ± 7.2A0.226 ± 0.017C4.71 ± 1.51A0.092 ± 0.013B
C+Yes129.2 ± 21.2C45.8 ± 8.4B0.189 ± 0.041BC4.47 ± 1.23A0.254 ± 0.084A
F+Yes108.1 ± 8.5C32.9 ± 11.6AB0.132 ± 0.018A2.24 ± 0.82B0.222 ± 0.035A
Fa+Yes55.3 ± 16.6AB24.7 ± 4.4A0.196 ± 0.038BC3.13 ± 0.73AB0.077 ± 0.021B

C−: control; F−: fructose; Fa−: high fat; C+: Cornus with control; F+: Cornus with fructose; (Fa+): Cornus with high fat.