The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats
Table 2
Activity of oxidative stress markers (CAT, PON1, FRAP, PCG, and SH) marked in brain tissue homogenates in Wistar rats. Data are presented as means from independent measurements ± standard deviation (SD). Different letters in the same columns indicate significant differences according to Tukey’s test ().
Diet
Cornus
CAT-brain U/mg protein
PON1-brain U/mg protein
FRAP-brain mM Fe2+/mg protein
PCG-brain nM/mg protein
SH-brain nM/mg protein
C−
No
65.4 ± 17.9B
31.8 ± 14.3AB
0.112 ± 0.015A
3.4 ± 1.47AB
0.225 ± 0.091A
F−
No
53.5 ± 20.6AB
20.7 ± 6.5A
0.168 ± 0.044AB
4.28 ± 1.37AB
0.317 ± 0.089A
Fa−
No
32.2 ± 13.7A
17.1 ± 7.2A
0.226 ± 0.017C
4.71 ± 1.51A
0.092 ± 0.013B
C+
Yes
129.2 ± 21.2C
45.8 ± 8.4B
0.189 ± 0.041BC
4.47 ± 1.23A
0.254 ± 0.084A
F+
Yes
108.1 ± 8.5C
32.9 ± 11.6AB
0.132 ± 0.018A
2.24 ± 0.82B
0.222 ± 0.035A
Fa+
Yes
55.3 ± 16.6AB
24.7 ± 4.4A
0.196 ± 0.038BC
3.13 ± 0.73AB
0.077 ± 0.021B
C−: control; F−: fructose; Fa−: high fat; C+: Cornus with control; F+: Cornus with fructose; (Fa+): Cornus with high fat.