Research Article

The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats

Table 3

Activity of oxidative stress markers (CAT, PON1, FRAP, PCG, and SH) marked in plasma in Wistar rats. Data are presented as means from independent measurements ± standard deviation (SD). Different letters in the same columns indicate significant differences according to Tukey’s test ().

DietCornusCAT-plasma
U/mg protein
PON1-plasma
U/mg protein
FRAP-plasma 
mM Fe2+/mg protein
PCG-plasma
nM/mg protein
SH-plasma
nM/mg protein

C−No467.1 ± 56C336.3 ± 71.6AC0.326 ± 0.065A6.57 ± 1.94AB 2.554 ± 0.265A
F−No272.9 ± 21.7A263.1 ± 73BC0.388 ± 0.075A6.93 ± 1.96A4.017 ± 1.226A
Fa−No248 ± 23.4AB186.6 ± 23.1B0.417 ± 0.146A5.85 ± 0.64AB2.44 ± 0.642A
C+Yes304.1 ± 69.4A423.7 ± 98.8A0.413 ± 0.028A6.78 ± 0.85A2.179 ± 0.968A
F+Yes283.2 ± 41.8A407.6 ± 64.7A0.421 ± 0.085A4.12 ± 1.01B3.356 ± 2.697A
Fa+Yes188.6 ± 55.4B388.8 ± 58.1A0.406 ± 0.042A5.54 ± 1.85AB 2.026 ± 0.85A

C−: control; F−: fructose; Fa−: high fat; C+: Cornus with control; F+: Cornus with fructose; Fa+: Cornus with high fat.