Table 1: Macroscopic pathological lesions observed in chicks treated using different doses of Rhinella jimi venom.

Organs ChangesPoison dose (mg/kg)
0
( )
3
( )
6
( )
10
( )
25
( )

LiverHepatomegaly
Necrotic areas
0
0
5
5
5
5
5
5
5
5
**

SpleenSplenomegaly00355**

HeartSagging
Hydropericardium
Hemorrhagic areas
Necrosis
0
0
0
0
2
0
0
0
3
0
0
0
5
0
2
4
5
1
3
5
***
n.s.
**
***

Meckel’s diverticulumDark-colored necrosis00043**

LungsHemorrhage00245***

KidneysHemorrhage00255***

Chi-squared test for trend.
n.s.: nonsignificant; *: <0.05; **: <0.01; ***: <0.001.