Toxicity Effects of Toad (Rhinella jimi Stevaux, 2002) Venom in Chicken (Gallus gallus domesticus)

Table 1

Macroscopic pathological lesions observed in chicks treated using different doses of Rhinella jimi venom.

Organs	Changes	Poison dose (mg/kg)					𝑃^1
		0; (𝑁=3)	3; (𝑁=5)	6; (𝑁=5)	10; (𝑁=5)	25; (𝑁=5)
Liver	Hepatomegaly; Necrotic areas	0; 0	5; 5	5; 5	5; 5	5; 5	**
Spleen	Splenomegaly	0	0	3	5	5	**
Heart	Sagging; Hydropericardium; Hemorrhagic areas; Necrosis	0; 0; 0; 0	2; 0; 0; 0	3; 0; 0; 0	5; 0; 2; 4	5; 1; 3; 5	***; n.s.; **; ***
Meckel’s diverticulum	Dark-colored necrosis	0	0	0	4	3	**
Lungs	Hemorrhage	0	0	2	4	5	***
Kidneys	Hemorrhage	0	0	2	5	5	***

1Chi-squared test for trend.
n.s.: nonsignificant; *: <0.05; **: <0.01; ***: <0.001.