Association of Interleukin-18 Gene Polymorphism with Susceptibility to Visceral Leishmaniasis in Endemic Area of Bihar, an Indian Population

Table 3

IL-18 genotype and alleles frequencies in VL cases and controls.

Genotypes and alleles	Patient	(%)	Control	(%)		value	OR (95% CI)	Study power
+105
Genotypes
AA	114	55.88	145	54.31	0.116	0.7335	1.066 (0.739–1.538)	4.82%
CC	5	2.45	6	2.25	0.021	0.8846	1.093 (0.329–3.633)	2.68%
AC	85	41.67	116	43.45	0.149	0.6989	0.930 (0.643–1.345)	5.42%
Alleles
A	313	76.72	406	76.03	0.060	0.8062	1.039 (0.767–1.407)	3.70%
C	95	23.28	128	23.97
−656
Genotypes
GG	89	43.63	133	49.81	1.776	0.1827	0.780 (0.541–1.125)	26.42%
TT	61	29.90	23	8.61	35.76	<0.0001	4.525 (2.685–7.628)	100%
GT	54	26.47	111	41.57	11.59	<0.0007	0.506 (0.341–0.751)	93.11%
Alleles
G	232	56.86	377	70.60	19.1	<0.0001	0.549 (0.419–0.719)	99.20%
T	176	43.14	157	29.40
−137
Genotypes
GG	128	62.75	136	50.94	6.546	0.0105	1.622 (1.119–2.353)	72.77%
CC	13	6.37	19	7.12	0.101	0.7507	0.888 (0.428–1.844)	4.46%
GC	63	30.88	112	41.95	6.064	0.0138	0.618 (0.421–0.908)	69.55%
Alleles
G	319	78.19	384	71.91	4.812	0.0283	1.40 (1.036–1.893)	59.42%
C	89	21.81	150	28.09