Research Article
Association of Interleukin-18 Gene Polymorphism with Susceptibility to Visceral Leishmaniasis in Endemic Area of Bihar, an Indian Population
Table 4
Frequently occurrence of IL-18 single and double haplotypes distributions in cases and controls.
| | Haplotypes | Cases | Control | | value | OR (95% CI) | Study power |
| | Single haplotypes | | | | | | | | GGA | 67 (32.97) | 102 (38.31) | 1.444 | 0.2296 | 0.792 (0.54–1.161) | 22.12% | | TGA | 58 (28.33) | 39 (14.49) | 13.52 | 0.0002 | 2.333 (1.477–3.684) | 95.52% | | GCA | 23 (11.06) | 36 (13.67) | 0.5148 | 0.4731 | 0.785 (0.449–1.375) | 12.96% | | GGC | 19 (9.45) | 40 (14.94) | 3.39 | 0.0656 | 0.594 (0.334–1.058) | 42.71% | | TCA | 9 (4.35) | 26 (9.56) | 4.769 | 0.029 | 0.430 (0.196–0.945) | 58.07% | | TGC | 15 (7.43) | 11 (4.17) | 2.318 | 0.1279 | 1.845 (0.832–4.089) | 33.77% | | GCC | 7 (3.38) | 10 (3.68) | 0.03276 | 0.8564 | 0.916 (0.34–2.467) | 2.81% | | TCC | 6 (3.02) | 3 (1.18) | 2.038 | 0.1534 | 2.608 (0.663–10.263) | 30.53% | | Double haplotypes | | | | | | | | GGA/GGA | 22 (10.78) | 39 (14.61) | 1.49 | 0.22 | 0.70 (0.40–1.23) | 22.75% | | TGA/GGA | 38 (18.63) | 30 (11.24) | 5.11 | 0.02 | 1.80 (1.07–3.03) | 61.58% | | GCA/GGA | 15 (7.35) | 28 (10.49) | 1.36 | 0.242 | 0.67 (0.35–1.30) | 21.02% | | GGC/GGA | 13 (6.37) | 31 (11.61) | 3.74 | 0.052 | 0.05 (0.26–1.08) | 49.03% |
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