Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina

Table 3

Baseline characteristics of study patients.

Variable	All patients	Control	Vasospasm	𝑃 value
	𝑁=859	𝑁=401	𝑁=458
Age, years	58.0±12.1	56.7±12.6	59.5±11.6	0.001*
Men, 𝑛 (%)	538 (63%)	211 (50%)	327 (70%)	<0.001*
Body mass index, kg/m^2	26.2±3.9	26.1±4.3	26.2±3.6	0.629
Smoker, 𝑛 (%)	312 (36%)	106 (26%)	206 (45%)	<0.001*
Diabetes mellitus, 𝑛 (%)	189 (22%)	86 (21%)	103 (22%)	0.434
Arterial hypertension, 𝑛 (%)	404 (47%)	177 (44%)	227 (50%)	0.105
Peripheral white blood cell count, /1000 mm^3	7.13±2.19	6.57±1.78	7.52±2.41	<0.001*
Peripheral monocyte blood cell count, /mm^3	346±316	258±217	423±364	<0.001*
Haemoglobin, g/dL	13.6±1.6	13.2±1.8	13.7±1.7	<0.001*
Creatinine, mg/dL	1.2±0.3	1.3±1.8	1.1±0.9	0.049*
eGFR, mL/min/1.73 m^2	77.3±11.5	77.0±25.5	77.8±22.4	0.796
CKD stage				0.995
1, 𝑛, %	230	108 (27%)	122 (27%)
2, 𝑛, %	483	225 (56%)	258 (56%)
3, 𝑛, %	146	68 (17%)	78 (17%)
&hs-CRP, mg/L	4.4±6.5	2.8±3.4	5.4±7.7	<0.001*
Cholesterol, mg/dL	204.3±43.3	204.6±45.0	203.2±42.5	0.633
Left ventricular ejection fraction, %	67±10	68±11	67±9	0.757
Systolic blood pressure, mmHg	131±19	131±20	132±19	0.64
Diastolic blood pressure, mmHg	77±12	78±12	77±11	0.295

Data are presented as mean ± standard deviation or number of patients (percentage).
^∗𝑃<0.05 between patients who did not have vasospasm and patients who did.
&Mann Whitney test was used to compare hs-CRP levels between groups due to that hs-CRP levels were not normally distributed.
Abbreviation: eGFR: estimated glomerular filtration rate; CKD: chronic kidney disease; hs-CRP: high sensitivity-C reactive protein.
Statistical significance based on Student’s 𝑡-test or chi-square test.