Antidiabetic Activity of Benzopyrone Analogues in Nicotinamide-Streptozotocin Induced Type 2 Diabetes in Rats

Figure 4

Determination of insulin tolerance (K-ITT) in normal and nicotinamide, STZ diabetic rats; first-order rate constant for the disappearance rate of glucose from plasma (K-ITT) upon insulin treatment (4 IU/kg, i.p.) was estimated from the slope of the regression line of the logarithmic plot of blood glucose (in mg/dL) against time. Slope is negative because blood glucose decreases with time after insulin. (G1: normal rats and G2: diabetes induced rats). The figure does not show the plots of all treated groups because values are close to each other and overlapping.