Lipophilicity Assessment of Ruthenium(II)-Arene Complexes by the Means of Reversed-Phase Thin-Layer Chromatography and DFT Calculations

Table 1

Calibration set of standard compounds with experimentally determined log𝐾_OW values.

No.	Compound	log𝐾OW	p𝐾𝑎	α Ionization degree (%)
1	1,2,3-Benzotriazole	1.44	8.37	0.42
2	4-Chlorobenzoic acid	2.65	3.98	99.05
3	2-Nitrobenzaldehyde	1.74	—	—
4	4-Bromoaniline*	2.26	3.86	99.28*
5	Phenol	1.46	10.09	0.01
6	Benzophenone	3.18	—	—
7	3-Nitrobenzaldehyde	1.46	—	—
8	4-Aminobenzoic acid	0.83	4.65	95.72
9	Phthalimide*	1.15		100.00*
10	1,4-Benzoquinone	0.20	—	—
11	4-Nitrophenol	1.91	7.15	6.61
12	3-Nitrophenol	2.00	8.28	0.52
13	Benzyl alcohol	1.10	—	—
14	Naphthylamine*	2.25	3.92	99.18*
15	2-Naphthol	2.85	9.67	0.02
16	4-Fluoroaniline*	1.15	4.70	95.23*
17	1-Naphthol	2.85	9.34	0.05
18	4-Hydroxybenzaldehyde	1.35	—	—
19	3-Chloronitrobenzene	2.46	—	—
20	2,4-Dichlorophenol	3.06	7.85	1.39
21	4-Methylphenol	1.94	10.09	0.01
22	4-Chlorophenol	2.39	9.38	0.04
23	Anthracene	4.45	—	—
24	Acetophenone	1.58	—	—
25	2-Aminophenol	0.62	9.44	0.04
26	4-t-Butylphenol	3.31	10.31	0.00
27	1,3,5-Trihydroxybenzene	0.16	9.40	0.04
28	2,6-Dimethylphenol	2.36	10.59	0.00

∗Calculated to the corresponding protonated conjugated acid.