Antinociceptive and Antioxidant Activity of Zanthoxylum budrunga Wall (Rutaceae) Seeds

Table 5

Effect of Z. budrunga seed extract in hot-plate test on mice.

Treatment (𝑛=6)	Dose (mg/kg)	Latency time (sec)
		0 min	30 min	60 min	90 min	120 min
Control	—	3.26±0.04	3.26±0.04	3.27±0.08	3.23±0.07	3.23±0.06
Morphine	5	3.61±0.03^∗	6.38±0.15^∗	7.38±0.13^∗	9.41±0.16^∗	8.30±0.10^∗
ZBSE	250	3.74±0.05^∗	4.56±0.05^∗	5.90±0.09^∗	5.05±0.05^∗	4.50±0.15^∗
	500	3.82±0.04^∗	5.49±0.09^∗	6.61±0.07^∗	6.02±0.16^∗	5.00±0.16^∗

Values are expressed as mean ± standard error for mean, 𝑛: number of mice (6); ^∗𝑃<0.001 versus control (Student’s t-test).