4-Hydroxy-2-nonenal Induces Apoptosis by Inhibiting AKT Signaling in Human Osteosarcoma Cells
Figure 1
4-HNE induces cell apoptosis in MG63 cells. (a) Histograms showing the quantification of the cell death (%) in MG63 cells after 4-HNE treatment for 2 h and recovery for another 2 h. The final concentration of 4-HNE ranges from 1 to 50 μM. Results are averages of three independent experiments. (b) Histograms showing the quantification of the cell death (%) in MG63 cells after 50 μM 4-HNE treatment for different time points, from 0.5 to 4 h. Results are averages of three independent experiments.
