Glycogen Synthase Kinase-3 Regulates Production of Amyloid-β Peptides and Tau Phosphorylation in Diabetic Rat Brain

Figure 2

The activity of GSK-3. The activities of GSK-3 in hippocampal extracts from rats injected with STZ, STZ plus NaCl, or STZ plus LiCl were determined by using specific peptide substrates. ^∗∗𝑃<0.01 versus control group, ^##𝑃<0.01 versus DM group.