The Feasibility of Using CT-Guided ROI for Semiquantifying Striatal Dopamine Transporter Availability in a Hybrid SPECT/CT System

Figure 1

Regions of interest (ROIs) were manually drawn directly on the summed SPECT image (a). In CT-guided method, ROIs were manually delineated directly on one CT slice with the best recognizable striatum. ROIs were then transferred to the hardware-based coregistered summed SPECT image (b, c). In MRI-guided method, ROIs were manually delineated directly on one MRI slice with the best recognizable striatum. ROIs were then transferred to the software-based coregistered summed SPECT image (d, e).