Table of Contents Author Guidelines Submit a Manuscript
The Scientific World Journal
Volume 2014, Article ID 892091, 4 pages
http://dx.doi.org/10.1155/2014/892091
Research Article

Cardiometabolic Risk Factors in Patients with Erectile Dysfunction

1Department of Urology, Bozok University, School of Medicine, Yozgat, Turkey
2Department of Cardiology, Bozok University, School of Medicine, Yozgat, Turkey
3Department of Cardiovascular Surgery, Bozok University, School of Medicine, Yozgat, Turkey
4Department of Internal Medicine, Bozok University, School of Medicine, Yozgat, Turkey

Received 28 August 2013; Accepted 6 November 2013; Published 22 January 2014

Academic Editors: J. R. Correa-Pérez and R. L. Davis

Copyright © 2014 Serhat Tanik et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. P. Gupta, M. H. Murad, M. M. Clifton, L. Prokop, A. Nehra, and S. L. Kopecky, “The effect of lifestyle modification and cardiovascular risk factor reduction on erectile dysfunction: a systematic review and meta-analysis,” Archives of Internal Medicine, vol. 171, no. 20, pp. 1797–1803, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. G. Jackson, “The importance of risk factor reduction in erectile dysfunction,” Current Urology Reports, vol. 8, no. 6, pp. 463–466, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. J. B. Kostis, G. Jackson, R. Rosen et al., “Sexual dysfunction and cardiac risk (the Second Princeton Consensus Conference),” American Journal of Cardiology, vol. 96, no. 2, pp. 313–321, 2005. View at Publisher · View at Google Scholar · View at Scopus
  4. K. L. Billups, A. J. Bank, H. Padma-Nathan, S. Katz, and R. Williams, “Erectile dysfunction is a marker for cardiovascular disease: results of the Minority Health Institute Expert Advisory Panel,” Journal of Sexual Medicine, vol. 2, no. 1, pp. 40–50, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. R. Virag, P. Bouilly, and D. Frydman, “About arterial risk factors and impotence,” The Lancet, vol. 1, no. 8437, pp. 1109–1110, 1985. View at Google Scholar · View at Scopus
  6. T. Coutinho, K. Goel, D. Corrêa De S et al., “Central obesity and survival in subjects with coronary artery disease: a systematic review of the literature and collaborative analysis with individual subject data,” Journal of the American College of Cardiology, vol. 57, no. 19, pp. 1877–1886, 2011. View at Publisher · View at Google Scholar · View at Scopus
  7. C. J. Lavie, R. V. Milani, S. M. Artham, D. A. Patel, and H. O. Ventura, “The obesity paradox, weight loss, and coronary disease,” American Journal of Medicine, vol. 122, no. 12, pp. 1106–1114, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. R. L. Kolotkin, C. Zunker, and T. Ostbye, “Sexual functioning and obesity: a review,” Obesity, vol. 20, no. 12, pp. 2325–2333, 2012. View at Google Scholar
  9. J. Fillo, J. Breza, M. Levčíkova et al., “Occurrence of erectile dysfunction, testosterone deficiency syndrome and metabolic syndrome in patients with abdominal obesity. Where is a sufficient level of testosterone?” International Urology and Nephrology, vol. 44, no. 4, pp. 1113–1120, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. P. M. Janiszewski, I. Janssen, and R. Ross, “Abdominal obesity and physical inactivity are associated with erectile dysfunction independent of body mass index,” Journal of Sexual Medicine, vol. 6, no. 7, pp. 1990–1998, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. G. Iacobellis, D. Corradi, and A. M. Sharma, “Epicardial adipose tissue: anatomic, biomolecular and clinical relationships with the heart,” Nature Clinical Practice Cardiovascular Medicine, vol. 2, no. 10, pp. 536–543, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. T. Mazurek, L. Zhang, A. Zalewski et al., “Human epicardial adipose tissue is a source of inflammatory mediators,” Circulation, vol. 108, no. 20, pp. 2460–2466, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. G. Iacobellis, M. C. Ribaudo, F. Assael et al., “Echocardiographic epicardial adipose tissue is related to anthropometric and clinical parameters of metabolic syndrome: a new indicator of cardiovascular risk,” Journal of Clinical Endocrinology and Metabolism, vol. 88, no. 11, pp. 5163–5168, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. A. E. Malavazos, F. Ermetici, E. Cereda et al., “Epicardial fat thickness: relationship with plasma visfatin and plasminogen activator inhibitor-1 levels in visceral obesity,” Nutrition, Metabolism and Cardiovascular Diseases, vol. 18, no. 8, pp. 523–530, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Kremen, M. Dolinkova, J. Krajickova et al., “Increased subcutaneous and epicardial adipose tissue production of proinflammatory cytokines in cardiac surgery patients: Possible role in postoperative insulin resistance,” Journal of Clinical Endocrinology and Metabolism, vol. 91, no. 11, pp. 4620–4627, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. G. Iacobellis, E. Lonn, A. Lamy, N. Singh, and A. M. Sharma, “Epicardial fat thickness and coronary artery disease correlate independently of obesity,” International Journal of Cardiology, vol. 146, no. 3, pp. 452–454, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. G. Iacobellis and A. C. Bianco, “Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features,” Trends in Endocrinology and Metabolism, vol. 22, no. 11, pp. 450–457, 2011. View at Publisher · View at Google Scholar · View at Scopus
  18. R. C. Rosen, J. C. Cappelleri, M. D. Smith, J. Lipsky, and B. M. Peñ, “Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction,” International Journal of Impotence Research, vol. 11, no. 6, pp. 319–326, 1999. View at Google Scholar · View at Scopus
  19. G. Iacobellis, F. Assael, M. C. Ribaudo et al., “Epicardial fat from echocardiography: a new method for visceral adipose tissue prediction,” Obesity Research, vol. 11, no. 2, pp. 304–310, 2003. View at Google Scholar · View at Scopus
  20. M. E. Sullivan, S. R. Keoghane, and M. A. W. Miller, “Vascular risk factors and erectile dysfunction,” BJU International, vol. 87, no. 9, pp. 838–845, 2001. View at Publisher · View at Google Scholar · View at Scopus
  21. T. Roumeguère, E. Wespes, Y. Carpentier, P. Hoffmann, and C. C. Schulman, “Erectile dysfunction is associated with a high prevalence of hyperlipidemia and coronary heart disease risk,” European Urology, vol. 44, no. 3, pp. 355–359, 2003. View at Publisher · View at Google Scholar · View at Scopus
  22. H. Solomon, J. W. Man, and G. Jackson, “Erectile dysfunction and the cardiovascular patient: endothelial dysfunction is the common denominator,” Heart, vol. 89, no. 3, pp. 251–254, 2003. View at Google Scholar · View at Scopus
  23. A. M. Traish, R. J. Feeley, and A. Guay, “Mechanisms of obesity and related pathologies: androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction,” FEBS Journal, vol. 276, no. 20, pp. 5755–5767, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. G. Iacobellis and G. Barbaro, “The double role of epicardial adipose tissue as pro- and anti-inflammatory organ,” Hormone and Metabolic Research, vol. 40, no. 7, pp. 442–445, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. N. Singh, H. Singh, H. K. Khanijoun, and G. Iacobellis, “Echocardiographic assessment of epicardial adipose tissue—a marker of visceral adiposity,” McGill Journal of Medicine, vol. 10, no. 1, pp. 26–30, 2007. View at Google Scholar · View at Scopus
  26. A. R. Baker, N. F. da Silva, D. W. Quinn et al., “Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease,” Cardiovascular Diabetology, vol. 5, article 1, 2006. View at Publisher · View at Google Scholar · View at Scopus
  27. S. Eroglu, L. E. Sade, A. Yildirir et al., “Epicardial adipose tissue thickness by echocardiography is a marker for the presence and severity of coronary artery disease,” Nutrition, Metabolism and Cardiovascular Diseases, vol. 19, no. 3, pp. 211–217, 2009. View at Publisher · View at Google Scholar · View at Scopus
  28. G. Iacobellis, A. M. Pellicelli, A. M. Sharma, B. Grisorio, G. Barbarini, and G. Barbaro, “Relation of subepicardial adipose tissue to carotid intima-media thickness in patients with human immunodeficiency virus,” American Journal of Cardiology, vol. 99, no. 10, pp. 1470–1472, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. F. Natale, M. A. Tedesco, R. Mocerino et al., “Visceral adiposity and arterial stiffness: echocardiographic epicardial fat thickness reflects, better than waist circumference, carotid arterial stiffness in a large population of hypertensives,” European Journal of Echocardiography, vol. 10, no. 4, pp. 549–555, 2009. View at Publisher · View at Google Scholar · View at Scopus
  30. S.-G. Ahn, H.-S. Lim, D.-Y. Joe et al., “Relationship of epicardial adipose tissue by echocardiography to coronary artery disease,” Heart, vol. 94, no. 3, article e7, 2008. View at Google Scholar · View at Scopus